What is sickle cell anemia?
Advisory Board of the Central Homeopathic Research Council, Ministry of AYUSH (Government of India) and the Executive Council of DAVV Indore, Hemopathic Dr. AK Dwivedi says that A sickle cell is a red blood cell that is abnormally shaped like a sickle or crescent moon. Sickle cells are stiff and sticky, and they can block blood flow to different parts of the body. This can cause a variety of health problems, including pain, anemia, stroke, and organ damage.
Sickle cell disease is a group of inherited blood disorders that cause people to have sickle cells. It is caused by a mutation in the gene that codes for hemoglobin, the protein in red blood cells that carries oxygen. Normally, red blood cells are round and flexible, and they can easily move through the blood vessels. However, in people with sickle cell disease, the abnormal hemoglobin causes the red blood cells to become sickle-shaped.
Sickle cell disease is a lifelong condition, and there is no cure. However, there are treatments that can help to manage the symptoms and prevent complications.
How does sickle cell disease occur and its types?
Advisory Board of the Central Homeopathic Research Council, Ministry of AYUSH (Government of India) and the Executive Council of DAVV Indore, Hemopathic Dr. AK Dwivedi say’s This disease is genetic based. Every person inherits one gene from his parents. That means every person has two genes, one is received from the mother while the other is received from the father. This gene may have normal Hb-A type of hemoglobin, or one may have normal and the other abnormal Hb-S type of hemoglobin, or both genes may have abnormal Hb-S type of hemoglobin. Red blood cells with abnormal type of hemoglobin are called sickle cells. People who have this type of gene can inherit any of these genes to their children in the future, which can be normal Hb-A or abnormal Hb-S. There are two types of sickle cell anemia. The first type is called sickle carrier in English. In which the evidence of abnormal hemoglobin Hb-S is less than 50% and the evidence of normal Hb-A is more than 50%. Whereas the second type is called a person suffering from sickle, in which the evidence of abnormal hemoglobin Hb-S is more than 50%, about 80% and normal hemoglobin is not present at all.
First type i.e. sickle cell carrier: People act as carriers of the disease, that is, the symptoms of sickle cell disease are not permanent but appear occasionally. Still, these people can pass on this hereditary disease to their children.
Second type of sickle patients: These are those people in whom the symptoms of the disease remain permanently, due to which the development of their body stops. These people definitely pass on this hereditary disease to their children.
How is this disease genetic?
• If the mother and father do not have sickle cell trait or sickle cell disease, then their children do not get this disease. That is, children of parents having normal hemoglobin do not get this disease and hereditary children have normal hemoglobin.
• If either the mother or father is a sickle carrier, then there is a 50% chance of the children being sickle carriers and 50% of the children having normal traits. But none of these children suffer from sickle disease.
• If both parents are sickle carriers, then 25% of their children are likely to be sickle disease, 50% children are sickle carriers and only 25% are normal children.
• If one of the parents has sickle disease and the other person is normal, then it is 100% that means all children can be sickle carriers but not sickle disease.
• If one person from both the parents is sickle disease and one person is sickle carrier then 50% of their children will be sickle disease and 50% children will be sickle carrier.
• If both the parents are suffering from sickle disease then 100% i.e. all the children will be born with sickle disease.
what can we do
Accepting the reality, while getting married we should ensure that,
• Both the persons getting married should not be sickle carriers or sickle disease.
• If one of the two people is a sickle cell carrier, or one of them has sickle cell disease, then children cannot have sickle cell disease. But there is only a possibility of being a sickle cell carrier.
Therefore, it would be appropriate to get a blood test done in the hospital and choose a suitable life partner and get married.
What are the symptoms of a patient with sickle cell disease?
Advisory Board of the Central Homeopathic Research Council, Ministry of AYUSH (Government of India) and the Executive Council of DAVV Indore, Hemopathic Dr. AK Dwivedi says Swelling or pain in the joints, gallstones, frequent fever or cold, enlargement of the spleen, swelling on the liver, poor growth of children, the easy occurrence of other diseases due to decreased immunity, etc., are the causes of this disease. Symptoms If the disease is not diagnosed, the child may die in childhood due to lack of necessary treatment.
After knowing all this, it is important to pay attention to some things such as:
• Before marriage, get the blood of the boy and girl tested for sickle cell.
• If any member in the family has sickle cell anemia, then get the sickle cell blood test of all the family members done.
• If you are a sickle cell patient (diagnosed after a blood test), then when you go to the doctor to get medicine, inform the doctor about your disease so that you can get the necessary medicines and treatment.
• Remember, sickle bearer is not a patient, but a sickle carrier, while sickle disease is a disease. Both these conditions are inherited by children from their parents.
• If you have frequent jaundice, anemia, joint pain or experience yellowness on the face, get your blood tested in a hospital.
• If a sickle carrier or a person with the sickle disease is married to another sickle carrier or a person with the sickle disease and the woman is pregnant, then whether the children will have this disease or not can be tested by taking a sample from 10 to 12 weeks of pregnancy. If there is a possibility of the child being born with sickle disease then abortion can be done.
What kind of precautions should be taken by people suffering from this disease
• Every sickle cell anemia patient should drink as much water as possible throughout the day (drink at least 10 to 15 glasses of water).
• One tablet of folic acid (5 mg) must be taken daily. Which will reduce anemia and help in creating new red blood cells in the blood.
• If excess water is lost from the body through vomiting, diarrhea and sweating, contact the doctor immediately.
• One should not consume alcohol, smoking or other intoxicating substances.
• If there is any problem, contact the doctor.
• A sickle cell patient should take a completely balanced diet/food so that he can get all the vitamins that are lacking in the body.
• Patients with sickle cell anemia have their hemoglobin levels and white blood cell counts measured regularly every three months.
What a person with sickle cell should not do
• Do not go out in extreme heat or sunlight
• Do not go to high-altitude mountains and hill stations
• Do not go out in extreme cold
• If there is a severe problem, do not try home remedies and consult a doctor in the hospital.